AKOS 43

AKOS 43 - Names and Identifiers

Name	4-tert-Butylcalix[4]arene
Synonyms	AKOS 43 LABOTEST-BB LT00453198 4-T-BUTYLCALIX[4]ARENE P-TERT-BUTYLCALIX[4]ARENE 4-TERT-BUTYLCALIX[4]ARENE 4-tert-Butylcalix[4]arene TETRA-TERT-BUTYL(TETRAHYDROXY)CALIX[4]ARENE 5,11,17,23-tetra-tert-butylpentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,26,27,28-tetrol 5,11,17,23-Tetratert-butylpentacyclo(19.3.1.1(3,7).1(9,13).1(15,19))octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,26,27,28-tetrol 5,11,17,23-Tetratert-butylpentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,26,27,28-tetrol 5,11,17,23-Tetra-tert-butylpentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-25,26,27,28-tetrol Pentacyclo[19.3.1.1(3,7).1(9,13).1(15,19)]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-25,26,27,28-tetrol, 5,11,17,23-tetrakis(1,1-dimethylethyl) Pentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-25,26,27,28-tetrol, 5,11,17,23-tetrakis(1,1-dimethylethyl)- ETHYL 2-([5,11,17,23-TETRA(TERT-BUTYL)-26,27,28-TRIS(2-ETHOXY-2-OXYETHOXY)PENTACYCLO[19.3.1.1(3,7).1(9,13).1(15,19)]OCTACOSA-1(25),3(28),4,6,9(27),10,12,15,17,19,(26),21,23-DODECAEN-25-YL]OXY)ACETATE
CAS	60705-62-6
EINECS	612-010-8
InChI	InChI=1/C44H56O4/c1-41(2,3)33-17-25-13-27-19-34(42(4,5)6)21-29(38(27)46)15-31-23-36(44(10,11)12)24-32(40(31)48)16-30-22-35(43(7,8)9)20-28(39(30)47)14-26(18-33)37(25)45/h17-24,45-48H,13-16H2,1-12H3
InChIKey	NVKLTRSBZLYZHK-UHFFFAOYSA-N

AKOS 43 - Physico-chemical Properties

Molecular Formula	C44H56O4
Molar Mass	648.91
Density	0.9543 (rough estimate)
Melting Point	≥300°C(lit.)
Boling Point	636.8°C (rough estimate)
Flash Point	252.6°C
Water Solubility	Soluble in chloroform, benzene, toluene. Insoluble in water.
Vapor Presure	2.73E-19mmHg at 25°C
Appearance	Crystalline Powder or Flakes
Color	White to light beige
BRN	2033965
pKa	9.53±0.20(Predicted)
Storage Condition	Store below +30°C.
Refractive Index	1.6400 (estimate)
MDL	MFCD00066280

AKOS 43 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29072990

AKOS 43 - Introduction

4-tert-Butylcalix[4]arene(4-tert-Butylcalix[4]arene) is an organic compound that belongs to the group of calixarenes. It has a structure in which four benzene rings are linked together by oxygen atoms, and each benzene ring has a tert-butyl functional group.

The following are some of the properties of 4-tert-Butylcalix[4]arene:
-Stability: It is stable at room temperature and is not sensitive to air and humidity.
-Solubility: It can be dissolved in organic solvents, such as chloroform, dimethyl sulfoxide and chlorinated methane.
-Melting point and boiling point: 4-tert-Butylcalix[4]arene has a melting point of about 200-210°C and a boiling point of about 350-400°C.

4-tert-Butylcalix[4]arene has many uses:
-Drug delivery system: It can be used as a carrier for drug molecules, containing drug molecules inside for more effective delivery through cell membranes.
-Ion recognition: It can identify and bind specific ions, so it has application potential in chemical sensors and separation science.

The preparation of 4-tert-Butylcalix[4]arene is as follows:
A commonly used method is to form the corresponding monomer through a condensation reaction under appropriate conditions. The reaction is usually carried out at elevated temperature and under acidic conditions. For example, 4-tert-Butylcalix[4]arene can be prepared by the condensation reaction of p-cresol and formaldehyde.

Regarding safety information, according to current research, 4-tert-Butylcalix[4]arene is considered relatively safe under general conditions of use. However, as with any chemical, use appropriate laboratory safety measures, including wearing appropriate protective equipment, avoiding contact with skin, and avoiding inhalation and ingestion. It should be noted that laboratories using 4-tert-Butylcalix[4]arene should evaluate and take appropriate safety measures according to their specific conditions.

Last Update：2024-04-09 20:49:11